The patients with the type I and the type II diabetes keep the check on the blood sugar levels via the regular finger pricks as well as need regular insulin injections. And apart from the pain and the repetitive and injecting a wrong dose of the medication would lead to more complications.
Researchers Developed Smart Patch:
The researchers from a University of the North Carolina and the NC state now developed the smart patch which would reject a requirement for the painful injections as well as the multiple finger pricks by just automatically delivering the insulin as possible. A paper, declared online in a PNAS (Proceedings of a National Academy of the Sciences), it describes a development of a micro array needle patch from the non toxic and the biocompatible materials. A system mimics glucose regulators, which are natural, and the pancreatic beta cells that act as the warehouses and the factories to make and also storing the insulin in the small vesicles.
The vesicles made by a team have the sensor molecules which will detect a level of the glucose and also deliver the insulin when a level is high and potentially rejecting a possibility of the overdose. When tested in the mouse model of the type I diabetes against the regular injection of the insulin, a patch produced the superior results as well as a regulated blood glucose level for thirty minutes and also maintained the level for more hours.
Smart Insulin Patch In Diabetic Patients:
Since the humans are very sensitive to insulin than the mice, all of the researchers trust that a patch can actually work in the long in the humans. An eventual goal to develop the smart insulin patch in the diabetic patients, which could be alternates once each and every few days. The microneedle array patches are loaded with the hypoxia sensitive vesicles give a fast glucose responsive insulin delivery.
The glucose responsive, that is close loop insulin delivery system mimicking a function of the pancreatic cells have the tremendous potential to develop the quality of the life and also health in the diabetics. They report that novel glucose responsive insulin delivery using the painless microneedle array patch that containing the glucose responsive vesicles that are loaded with the insulin and the glucose oxidase enzyme. Most of the patients get this treatment and then get a good health of their body and they have all completely believed it.